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Principal Investigator
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Address
MPI-BI
Am Klopferspitz 18
82152 Planegg-Martinsried
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Email
lisa.fenk[at]bi.mpg.de
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Research Topics
Sensory perception is often an active process, and many animal species move their sensory organs to control their interaction with the outside world. Fruit flies move their retinas, via tiny muscles, both seemingly spontaneously and in response to visual motion. These movements and our vertebrate eye movements share surprising similarities. We now leverage fly retinal movements as a relatively simple model to examine cellular underpinnings of active visual processing. We aim to understand how fly eye movements are controlled neuronally, how the brain deals with input provided by moving eyes, and how visual perception in the end benefits from eye movements.
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Scientific Approach
We use a variety of approaches in Drosophila, including quantitative behaviour, connectomics, genetic perturbations, electrophysiology and calcium imaging. We combine our efforts in Drosophila with comparative experiments in other insect species.
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Related Publications
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| Fenk LM, Avritzer, SC, Weisman, JL, Nair, A, Randt LD, Mohren, TL, Siwanowicz, I, Maimon, G. Muscles
that move the retina augment compound eye vision in Drosophila. Nature (2022) |
| Fenk LM*, Kim, AJ*, Maimon, G. Suppression of motion vision during course-changing, but not
course-stabilizing, navigational turns. Curr. Biol. (2021) |
| Kim AJ*, Fenk LM*, Lyu C, Maimon G. Quantitative predictions orchestrate visual signaling in Drosophila.
Cell (2017) |
| Fenk LM*, Poehlmann A*, Straw AD. Asymmetric processing of visual motion for simultaneous object and
background responses. Curr. Biol. (2014) |
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